Hyperthermia: Advanced Immune Boost
At CMN Hospital, our Advanced Cancer Treatment (ACT) program includes hyperthermia as an integral component of our comprehensive cancer treatment protocol. Hyperthermia involves elevating the body's temperature to treat cancer by damaging or destroying tumors using heat. This treatment mimics the body’s natural fever response, which is a crucial part of the immune system’s defense mechanism.
During a fever, elevated temperatures enhance the activity of immune cells such as macrophages, dendritic cells, T-cells, and B-cells. These cells become more efficient at eliminating pathogens and stimulating an adaptive immune response. Similarly, hyperthermia boosts immune function, improving the body's ability to recognize and attack cancer cells while directly damaging the cancer cells through heat exposure.
Local Hyperthermia
According to the American Cancer Society, local hyperthermia treatment occurs when "very high temperatures are used to kill the cancer cells and destroy nearby blood vessels. In effect, this cooks the area that is exposed to the heat." Local hyperthermia treatments utilize energy sources like microwave, radio-frequency, and ultrasound to apply heat to tumors. Depending on the tumor’s location, this treatment can be applied externally or internally, targeting tumors in or near the skin, body cavities, or deep within the body.
Regional Hyperthermia
Regional hyperthermia differs from local hyperthermia by applying heat to larger tissue areas, such as a limb or organ. One approach to regional hyperthermia involves deep tissue hyperthermia, which uses devices on the surface of the organ or body cavity to produce radiofrequency or microwave energy directed at the targeted area. Regional hyperthermia is highly effective for tumors located within organs or body cavities that require more expansive heat exposure.
Mechanism of Action
Hyperthermia is an advanced treatment that strengthens the immune system at various levels, enhancing the body's ability to fight infections and cancer cells. In response to elevated temperatures, immune cells such as macrophages and dendritic cells increase their activity, making them more effective in eliminating pathogens. T-cells and B-cells, key players in the adaptive immune system, are also activated during hyperthermia, further enhancing the body’s defense mechanisms.
Hyperthermia treatment is highly adaptable, with techniques that can be applied locally or regionally, depending on the patient’s specific medical condition. At CMN Hospital, hyperthermia is seamlessly integrated into each patient’s overall treatment plan, offering a personalized approach to cancer care.
Safety of Hyperthermia
The safety of hyperthermia treatments is well-documented. When administered under professional medical supervision, hyperthermia is a safe and effective treatment. Side effects are generally mild and may include skin redness, discomfort at the treatment site, and in rare cases, burns. Advanced monitoring techniques and precision equipment ensure that the temperature is controlled accurately, minimizing any risks. Clinical studies, including those published in the International Journal of Hyperthermia, support the safe use of hyperthermia in combination with other cancer treatments, highlighting its role as a valuable adjunct therapy.